What it is
Kisspeptin is a human hormone, encoded by the KISS1 gene. The form usually sold is kisspeptin-10, a ten-amino-acid fragment of it.
Unlike most entries in this library, this is not an invented molecule. It is a piece of ordinary human physiology that was identified relatively recently and turned out to be more important than anyone expected.
What it does
It is the switch at the top of the reproductive cascade.
Kisspeptin signals the release of gonadotropin-releasing hormone. That drives luteinising hormone and follicle-stimulating hormone. Those drive testosterone and oestrogen.
Everything downstream depends on this signal. That is why kisspeptin is a serious research subject, and also why it is sold with hormone and libido claims attached.
The fact most listings leave out
Kisspeptin-10 is on the FDA's current Category 2 list of bulk drug substances that may present significant safety risks in compounding under section 503A. It was added on 2023-09-29 and it is still there (page content current as of 2026-04-22).
This is worth pausing on, because it is genuinely unusual. Most compounds in this library appear on that page only under nominations that were withdrawn — which means no decision was ever reached — or they do not appear at all. Kisspeptin-10 was assessed and listed, and remains listed.
That is a narrow finding: it concerns pharmacies compounding the substance into preparations for patients. It is not a general ban and it is not a criminal matter. But it is a live restriction based on an actual safety assessment, which is more than can be said about most of this catalogue.
Real research, different questions
Genuine human clinical research on kisspeptin exists, largely in reproductive medicine. That sets it apart from most compounds sold in the same catalogues, and it means citations offered for it are often real.
The gap is between what that research asked and what the listings claim. Studies designed to understand reproductive signalling, or to investigate fertility, are not studies of hormone optimisation in healthy adults. A page can cite entirely genuine science and still be describing something the science never tested.
Where it stands
Approved as a medicine: nowhere, for anything.
FDA compounding status: kisspeptin-10 is currently listed in Category 2 (503A), added 2023-09-29.
Sold as: a research chemical, usually as kisspeptin-10.
Related entries in this library: gonadorelin is the next step down the same axis — the hormone kisspeptin causes to be released, and one that held two US approvals before both were discontinued. At the bottom of the same cascade, hCG stands in for luteinising hormone at the testes and ovaries, and it still has current US labels. Oxytocin is the other hypothalamic hormone in this library with an approved product and a much larger popular reputation than its trials support.
Last checked
2026-09-07.