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Pentadeca Arginate (PDA): What the Public Record Holds

PDA is marketed as an improved BPC-157. Its one public record is a 2013 patent on BPC-157's arginine salt; re-searched on 2026-10-07 it still has no PubChem record, no PubMed paper and no registered study.

One patent (US 9,850,282, priority 2013)No public structure recordNo registered studyNo published paper under any name form searchedSold as a research chemical

Caroline S · Published 2026-09-19 · Updated 2026-10-07

Length

15 residues, if the product is what the name says. The 2013 patent on BPC-157 salts describes the fifteen-residue BPC-157 chain paired with arginine; no public chemical database holds a structure record under the market name, so whether a given product matches the patent's compound is not checkable from the record.

Sequence

No sequence is recorded under the market name in any public chemical database: PubChem returned no CID for pentadeca arginate or pentadecapeptide arginate on 2026-10-07. The patent's compound is BPC-157 (GEPPPGKPADDAGLV) as a salt with basic amino acids, the di-L-arginine salt preferred; sellers describe PDA the same way.

Origin

Traces to a patent: US 9,850,282, 'Stable pentadecapeptide salts', Diagen d.o.o. of Slovenia, inventor Rudolf Rucman, priority date 13 March 2013, granted 26 December 2017. The patent calls the compound Arg-BPC; 'pentadeca arginate' is a later market name that does not appear in it.

Last reviewed

2026-10-07

What is it good for?

It is sold for the uses BPC-157 is sold for — tissue repair, gut, tendon and wound healing — with an added claim of greater stability. Those are seller claims. The stability claim has one source, the patent holder's own measurements; no published study, registered trial or regulatory record supports any of the uses, and none was found to contradict them either, because there is nothing there to contradict.

Illustration: An open blank lab notebook with a copper pen on a white lab bench, clean and unwritten.
Illustration

Pentadeca arginate — usually shortened to PDA — is sold in the research-chemical market as the next thing after BPC-157: the same peptide, the sellers say, in a more stable form. It arrived quickly and it is widely stocked.

This entry is short, because the public record on it is.

The one record that exists: a 2013 patent

The arginine salt of BPC-157 is described in US patent 9,850,282, "Stable pentadecapeptide salts", filed by Diagen d.o.o. of Slovenia, inventor Rudolf Rucman, priority date 13 March 2013, granted 26 December 2017 (Google Patents record, read 7 October 2026). It claims BPC-157 paired with one, two or three molecules of a basic amino acid and names the salt with two arginines, "Arg-BPC", as preferred. Its stated aim is oral use: it says the existing forms have inadequate stability in gastric juice.

The name "pentadeca arginate" does not appear in it. The patent's stability tables are the holder's own measurements and have not been replicated in any published paper found. PeptiFact's acetate-versus-arginate comparison works through those tables and the mass arithmetic of the two salts.

What was searched, and what came back

On 2026-09-19, and again on 2026-10-07, three kinds of public record were searched under every name form the compound is sold under.

Record Search terms Result
ClinicalTrials.gov pentadeca arginate · pentadecapeptide arginate 0 registrations
PubMed pentadeca arginate · pentadecapeptide arginate · arginate + BPC · arginine salt + BPC-157 0 records
PubChem pentadeca arginate · pentadecapeptide arginate No CID

That is an absence in all three at once — regulatory, bibliographic and chemical — with the patent the only document anywhere. It is worth saying why that combination is unusual. Plenty of compounds in this library have no clinical evidence; several have no registration. Very few have no structure record, because PubChem indexes molecules regardless of whether anyone has studied them. A compound with no CID is one that has not been deposited under that name by anyone at all.

What the name asserts

Two things, and both are worth separating from evidence.

Pentadeca- means fifteen. BPC-157 is a fifteen-residue peptide, so the name asserts the same chain length — the sequence GEPPPGKPADDAGLV, if it is in fact the same sequence.

Arginate names a salt form: the peptide supplied paired with arginine as its counter-ion, rather than the acetate that most research peptides are supplied as. A salt form is a real and ordinary thing. It changes how a powder dissolves, how it behaves in storage, and how much of the weighed mass is peptide. What it does not change is the amino acid sequence — the peptide inside is the same chain.

So the name, read carefully, claims a formulation difference rather than a new molecule — which is also what the patent describes. The marketing claim built on top of it — that the formulation difference produces a better result in a body — is a further step, and it is the step with nothing behind it: the patent measured stability, not effect.

The comparison the marketing invites

PDA is not sold as a new compound. It is sold as an improvement on a named one, which makes the comparison unavoidable. Here is what sits on the other side of it.

BPC-157 has a PubChem record (CID 9941957), 230 PubMed records and four ClinicalTrials.gov registrations as of 2026-09-19. That looks substantial next to zero. But reading those records rather than counting them: none of the 230 papers carries the clinical-trial publication type, and none of the four registrations has posted a result — two have not begun recruiting, one is filed under a product name and has carried the registry status UNKNOWN since 2015, and the one marked completed administered a consumer gummy product.

So the claim being made is that PDA improves on a compound whose own human evidence has not yet produced a single completed, published clinical result. Both sides of the comparison are weaker than the conversation around them suggests, and PDA's side holds one stability patent and no study.

How to read an absence

This library treats a documented absence as a finding rather than a gap, and the distinction is in whether the search is reproducible. The three searches above are stated in full, with their dates, so anyone can repeat them. This entry first said no record of any kind existed; the patent was missed because it never uses the market name, and the entry was corrected on 2026-10-07.

An absence is also not an accusation. Nothing here says PDA does not work, or that it is unsafe, or that the stability claim is false. It says that on the date searched, beyond the patent holder's own stability tables, no public record existed that would let anyone check — and that a compound sold on a comparison ought to be readable in the same places as the thing it is compared to.

Where it stands

PDA is not approved as a medicine in any country, and no regulatory filing for it was found. Material sold under the name carries a research-use label, which is a statement by the seller about what the product is sold for. It is not an approval, a safety finding or a quality standard, and no regulator has evaluated the substance because that label is on the bottle.

Related entries: the compound this one is sold against; KPV and the thymosin fragment sold for repair; and what "research use only" actually means, for the label on the vial.

What the research shows

PDA has been studied in people

ClinicalTrials.gov returned zero registrations for pentadeca arginate and zero for pentadecapeptide arginate on 2026-10-07

PDA has been studied in animals

PubMed returned zero records for pentadeca arginate, pentadecapeptide arginate, arginate BPC and arginine salt BPC-157 on 2026-10-07

PDA has a defined structure in a public chemical database

PubChem returned no CID for either name form on 2026-10-07; BPC-157 returns CID 9941957

Its stability advantage over BPC-157 acetate has been measured

Only in the 2013 patent, by the patent holder: after 90 days at 50 °C the solid arginine salt stayed 99.07% intact against 85.90% for the acetate. No independent replication and no paper was found. Stability in a vial is a chemistry result, not a measure of any effect in a body

The compound it is sold as an improvement on has clinical evidence

BPC-157 has 230 PubMed records and four registrations, but zero papers of clinical-trial publication type and no posted results on any registration

Bars show how much of the evidence is in humans, not how well anything works.

Frequently asked questions

What is pentadeca arginate?

A compound sold in the research-chemical market as an improved version of [BPC-157](/bpc-157). The name asserts two things: pentadeca- means fifteen, which is BPC-157's chain length, and arginate names a salt form in which the peptide is paired with arginine instead of the usual acetate. The salt itself is described in a 2013 patent, which calls it Arg-BPC; beyond that patent, no public chemical, bibliographic or regulatory record describing it was found on 2026-10-07.

Is there any research on it?

No study was found. PubMed returned zero records under four search forms, ClinicalTrials.gov zero registrations under two, and PubChem held no structure record, on 2026-10-07. The only measurements anywhere are the stability tables in the 2013 patent, made by the patent holder. That is stated here as a measured result rather than as an opinion about the compound.

Is it better than BPC-157?

More stable on the shelf, according to the patent holder's own tests; better in a body, unmeasured. The 2013 patent reports the arginine salt holding up far better than the acetate in heat and in mild acid, but at pH 2, close to an empty stomach, little of either was left after an hour. No study has compared the two for any effect. It is worth noting what the comparison is being made against: BPC-157 has 230 papers and four registrations, but zero published clinical trials and no posted results from any registration.

Does the salt form change the peptide?

Not the peptide itself. A salt form is the counter-ion supplied alongside the molecule; it affects handling, solubility and stability in storage, and it changes the mass of the supplied powder, but the amino acid sequence is unchanged. A claim that a different salt form makes a peptide work differently in the body is a separate claim and would need its own evidence.

Why does the absence matter rather than just being a gap?

Because of what the compound is sold as. A new compound with no record yet is ordinary. A compound marketed specifically as the better version of a named predecessor invites a comparison, and the comparison cannot be made: there is nothing on one side of it. The honest description is that PDA's advantages over BPC-157 are, as of 2026-09-19, unmeasured in public.

What would change this entry?

Any one of three things, all of them checkable: a PubChem or other public structure record defining the molecule; a PubMed-indexed paper reporting any experiment with it, in animals or in cells; or a ClinicalTrials.gov registration naming it. An independent replication of the patent's stability tables would also belong here. This entry states the searches used so that anyone can repeat them and see whether the answer has changed.