Selank Amidate: A Name With No Chemical Record and No Published Study

Selank amidate is sold as a capped version of Selank, the Russian anti-anxiety peptide, with an amide in place of the free acid at its end. PubChem has no record under the name, and PubMed has no paper that uses it. Every published Selank study tested the plain peptide. What the name would mean chemically, and what is not known.

Research-market nameNo PubChem record under this nameNo published study under this nameNot approved anywhere

Caroline S · Published 2026-10-02

Length

7 amino acids, the same as Selank, with the end carboxylic acid replaced by an amide, if the name is taken literally

Sequence

Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2, as the name implies. Selank's own PubChem record (CID 11765600) is the free acid: C33H57N11O9, molecular weight 751.9. Swapping the end -OH for -NH2 gives C33H58N12O8, about 750.9; that figure is our arithmetic, not a registered value

Origin

A name used on the research-chemical market. Unlike N-acetyl semax amidate, it has no PubChem record of its own (checked 2026-10-02)

Last reviewed

2026-10-02

What is it good for?

It is sold for the same purposes as Selank: anxiety, focus and mood. No study has tested anything under this name. Selank's own evidence, mostly Russian, was gathered on the plain peptide and does not transfer automatically to a different molecule.

Illustration

What the name means

Selank is a seven-amino-acid peptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, developed in Russia as an anti-anxiety drug and covered in full in this library's Selank entry. Its PubChem record (CID 11765600) is the free acid: the last proline ends in a carboxylic acid group (-COOH), formula C33H57N11O9, molecular weight 751.9.

"Amidate" on the research-chemical market means the end acid has been replaced by an amide (-CONH2). It is a common change in peptide drugs: many hormones carry it naturally, and it can slow breakdown by enzymes that attack a peptide's end. Taken literally, then, selank amidate would be:

	Selank (registered)	Selank amidate (implied by the name)
Sequence	TKPRPGP-OH	TKPRPGP-NH2
Formula	C33H57N11O9	C33H58N12O8
Molecular weight	751.9 (PubChem)	about 750.9 (our arithmetic)
Register record	CID 11765600	none found

What the registers show

PubChem returns no compound for "selank amidate", "selank amide" or "TKPRPGP-NH2" (checked 2026-10-02). That separates it from N-acetyl semax amidate, the double-capped semax variant, which does have a record, created in 2024 and deposited only by suppliers. Selank amidate has not reached even that stage.

What the literature shows

Nothing under this name. A PubMed search for "selank amidate" returned 2 records on 2026-10-02, but both are studies of plain Selank in rats (2003, PMID 14552529, and its 2002 Russian-language original, PMID 12449836). PubMed's own query translation shows it rewrote "amidate" into "amide" and related terms, so the matches came from the indexing, not from any amidated peptide. Neither paper mentions an amidated form.

PubMed's search for Selank returns 136 records, including two Russian trials in anxiety disorders tagged as randomised (2008, PMID 18454096; 2015, PMID 26356395). Every one tested the registered peptide. None of that evidence transfers automatically to a different molecule, however small the difference.

What is not known

Whether products sold under the name contain the amide, the free acid or something else. No published analysis was found.
Whether the amide cap changes how long the peptide lasts in the body, or what it does there.
Any safety data at all for the amidated form.

The parent peptide is Selank. The same naming pattern, with the same gap between name and evidence, appears on N-acetyl semax amidate and its parent semax. For how a peptide's two ends are built, see the peptide chain.

What the research shows

Works like Selank

No study found. PubMed returned 2 records for 'selank amidate' on 2026-10-02, and both are 2002–2003 rat studies of plain Selank. They matched only because PubMed rewrote 'amidate' to 'amide' and its related terms, as its query translation shows

The amide cap makes it last longer

No study of this molecule found. Capping a peptide's end is a general way of slowing its breakdown; whether it does so here has not been measured in anything published

Bars show how much of the evidence is in humans, not how well anything works.

Where it stands

Chemical registers

PubChem returns no compound for 'selank amidate', 'selank amide' or 'TKPRPGP-NH2' (2026-10-02). Selank's record, CID 11765600, is the free acid.

United States and EU

Not approved for any use. Selank itself is not approved either.

Published record

PubMed's Selank search returns 136 records (it also searches the code name TP-7); 2 are tagged as randomised controlled trials of Selank in anxiety (both Russian, 2008 and 2015); 0 that study the amidated form (2026-10-02).

Frequently asked questions

What is selank amidate?

A name used on the research-chemical market for Selank with an amide cap on its last amino acid. Taken literally, it is Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2. No chemical register holds a record under the name, and no published study uses it.

Is selank amidate the same as Selank?

Not if the name is accurate. Selank, as registered in PubChem, ends in a free acid. An amidated version is a different molecule, though only one atom group differs. A label alone cannot show which form a vial contains; only an analysis of the contents can.

Does selank amidate work better than Selank?

There is no evidence either way. No published study tests the amidated form. The claim that the cap makes it last longer is plausible chemistry but has not been measured for this peptide.

What does the research on Selank show?

Most of it is Russian. PubMed's Selank search returns 136 records, including two Russian anxiety trials tagged as randomised (2008 and 2015). This library's Selank entry covers that record and its limits.

Is selank amidate legal or approved?

Neither it nor Selank is approved for any use in the United States or the European Union.